Corso "Structure and Function of Proteins: Theory and Practice"

da Lunedì, 17 Giugno, 2024 - 10:00 a Venerdì, 21 Giugno, 2024 - 13:00
Prof. André Matagne
Laboratory of Enzymology and Protein Folding
Centre for Protein Engineering, University of Liège, Belgium
 
Optical properties of proteins and their applications in the study of protein folding, dynamics and stability
 
The objective of this course (approx. 10 hours) will be to illustrate how optical methods (UV-visible absorption, fluorescence, infrared and circular dichroism) can be used to study protein folding, dynamics and stability.

The course will include a review of the optical properties of proteins. Then, concrete examples (e.g. β-lactamases, single-domain antibody fragments, lysozymes) will be analysed in detail, on the basis of theoretical background (briefly reviewed during the course) and data found in the literature.